Pharmacokinetic/Pharmacodynamics Processing

Institute for Drug Development


Pharmacokinetic Sampling Department

The Pharmacokinetic Sampling Department (PSD) processes and ships all samples for Phase I and II trials conducted at the IDD. For the handling of samples, simple processes include centrifugation of the samples followed by the transfer of plasma or serum and then freezing. Complex processes, such as harvesting peripheral blood mononuclear cells using specialized tubes, and washing and storage medias, are also routinely performed in the laboratory.


The PSD also processes biopsies required by clinical trial protocols. A member of the PSD is present during biopsy procedures in order to immediately process and provide sponsors with the best possible sample.


The laboratory has up-to-date equipment that provides specialized services required by many sponsors. There are fixed angle and swing bucket centrifuges that can spin up to 4,000 g as well as a micro-centrifuge that can spin up to 14,000 g. The centrifuges have room temperature capabilities as well as cold temperature capabilities (0-4°C). Yearly maintenance and calibrations are conducted on the equipment in order to maintain accurate speeds and temperatures. The lab is also equipped with 5 freezers and a refrigerator (3 -80°C, one -40°C, and one -20°C) and a refrigerator / freezer which are monitored 24 hours a day, 7 days a week, by an Amegaview monitoring system.


For additional information, contact:

Yvette (Casarez) Skelton, BS
PSD Lab Manager
7979 Wurzbach Road, G352
San Antonio, TX 78229
Phone: (210) 450-1883
casarezy@uthscsa.edu