This Phase III study is for patients with pancreatic cancer who have had surgical resection. Patients will be randomized to receive adjuvant therapy, Gemcitabine or 5-FU chemoradiation with or without immunotherapy with HyperAcute Pancreatic Cancer Vaccine.
M402 is a heparin sulfate mimetic designed to have antitumor effect without the anticoagulant activity. In this Phase I/II study M402 is administered as daily subcutaneous injection with Gemcitabine in patients with metastatic pancreatic cancer who have not received prior chemotherapy.