Life Over Cancer
Cancer Therapy & Research Center
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EDT Research Projects


Primary Investigator Funding Agency Grant Number Start Date End Date Project Title Dir Cost Tot Cost % Prog Dir Prog Tot
Tyler Curiel Food and Drug Administration 7R01FD003118-02 3/15/2007 12:00:00 AM 3/14/2009 12:00:00 AM Phase II trial of ONTAK to treat ovarian cancer under BB-IND-12345 262757 350000 100 262757 350000
Tyler Curiel Fannie E. Rippel Foundation 1/1/2008 12:00:00 AM 1/7/2009 12:00:00 AM Regulatory T cells in ovarian cancer: biology and therapeutic potential 125000 125000 100 125000 125000
Francis Giles NCI 6U01CA069853-14 12/17/2007 12:00:00 AM 2/28/2009 12:00:00 AM Phase I clinical trials of anti-cancer agents 126293 179544 100 126293 179544
Francis Giles DOD W81XWH-08-2-0036 1/15/2007 12:00:00 AM 8/14/2009 12:00:00 AM A Molecular Oncology Program for Biomarker Discovery 890000 890000 100 890000 890000
Susan Mooberry NCI 5R01 CA21138-03 9/30/2006 12:00:00 AM 7/31/2011 12:00:00 AM The taccalonolides: mechanisms of action and cellular response 186302 275726 100 186302 275726
Susan Mooberry DOD W81XWH-08-1-0395 6/1/2008 12:00:00 AM 5/31/2011 12:00:00 AM Discovery of new therapeutic leads for prostate cancer 117160 173397 100 117160 173397
Shou-Jiang Gao NCI 5R01CA124332-02 4/1/2007 12:00:00 AM 1/31/2012 12:00:00 AM Regulation of KSHV infection and replication by MAPK pathways 190000 277400 100 190000 277400
Shou-Jiang Gao NCI 3R01CA124332-S1 3/1/2008 12:00:00 AM 2/28/2011 12:00:00 AM Regulation of KSHV infection and replication by MAPK pathways – Supplement 54628 80957 100 54628 80957
R. Aguiar American Society of Hematology NA 7/1/2007 12:00:00 AM 6/30/2009 12:00:00 AM Intersection of cAMP-PDE4B signals and survival pathways in beta cell lymphomas: transcriptional control and relevance for targeted therapy 49999 49999 100 49999 49999
R. Aguiar Elsa U. Pardee Foundation 1/1/2008 12:00:00 AM 12/31/2008 12:00:00 AM Interplay between JNK activity and micro RNA-155 expression in lymphomas 107200 134000 100 107200 134000
R. Aguiar Concern Foundation 7/1/2008 12:00:00 AM 6/30/2009 12:00:00 AM Regulation of micro RNA-155 expression in lymphomas 50000 50000 100 50000 50000
J. Agyin NCI 5K01CA113468-04 6/1/2005 12:00:00 AM 5/31/2010 12:00:00 AM Bone-seeking proteasome inhibitors for myeloma 135195 140240 100 135195 140240
A. Bao Susan G. Komen Breast Cancer Foundation BCTR070169 9/24/2007 12:00:00 AM 9/23/2009 12:00:00 AM Breast cancer brachytherapy using nanoparticle-carried therapeutic radionuclides 120449 150561 100 120449 150561
G. Fields NCI 2R01CA098799-06 4/1/2008 12:00:00 AM 3/31/2013 12:00:00 AM Mechanism and inhibition of collagenolytic activity 218530 302565 100 218530 302565
G. Fields NIH 5R01EB000289-08 8/25/2005 12:00:00 AM 6/30/2009 12:00:00 AM Peptide-amphiphile biomimetics for targeted therapies 191105 234448 100 191105 234448
J. Freeman VA-MERIT 3/1/2008 12:00:00 AM 2/28/2011 12:00:00 AM Role of RON kinase in pancreatic cancer 189000 189000 100 189000 189000
J. Freeman NCI 5R21CA125713-02 5/11/2007 12:00:00 AM 4/30/2009 12:00:00 AM Role of ErbB/STAT3 in the establishment and progression of pancreatic cancer 140000 204400 100 140000 204400
J. Freeman VA Merit Award 3/1/2008 12:00:00 AM 2/28/2011 12:00:00 AM Role of RON kinase in pancreatic cancer 189000 189000 100 189000 189000
G. Fullerton NIH 5T32EB000817-05 9/1/2004 12:00:00 AM 8/31/2009 12:00:00 AM Multidisciplinary training program in human imaging 233494 250697 100 233494 250697
R. Ghosh NCI 1R21 CA125719-01 6/1/2008 12:00:00 AM 5/31/2010 12:00:00 AM Role of E2F1 in eugenol-mediated anti-proliferative activity in melanoma cells 135000 195480 100 135000 195480
R. Ghosh NCI 1R03 CA136058-01 7/1/2008 12:00:00 AM 6/30/2010 12:00:00 AM Capsaicin for chemoprevention of transition cell carcinoma of the bladder 50000 74000 100 50000 74000
A. Hinck NIH 5R01GM058670-07 9/1/1999 12:00:00 AM 8/31/2010 12:00:00 AM Ligand-receptor interactions in the TGF-b superfamily 173639 253513 100 173639 253513
A. Hinck Welch Foundation AQ-1431 5/1/2008 12:00:00 AM 4/30/2011 12:00:00 AM Ligand-receptor interactions in the TGF-b superfamily 50000 50000 100 50000 50000
C. Keller NCI 1R01CA133229-01 4/22/2008 12:00:00 AM 1/31/2013 12:00:00 AM Therapeutic targets in alveolar rhabdomyosarcoma 207500 307100 100 207500 307100
C. Keller Numira Biosciences Inc 8/1/2007 12:00:00 AM 2/28/2009 12:00:00 AM Multi-platform (multiplat) reporter system 299745 359659 100 299745 359659
C. Keller Amschwand Sarcoma Cancer Foundation 12/15/2007 12:00:00 AM 12/14/2008 12:00:00 AM Role of platelet-derived growth factor receptor a in rhabdomyosarcoma 25000 25000 100 25000 25000
C. Keller Alex’s Lemonade Stand 7/1/2008 12:00:00 AM 6/30/2009 12:00:00 AM Therapeutics in Ovo 97875 97875 100 97875 97875
A. Kumar DOD W81XWH-04-1-0275 11/17/2005 12:00:00 AM 2/28/2009 12:00:00 AM Antioxidant prophylaxis in the prevention of prostatic epithelial neoplasia 57025 83226 100 57025 83226
A. Kumar ACS 04-169-01 7/1/2005 12:00:00 AM 6/30/2009 12:00:00 AM 2-Methoxyestradiol in prostate cancer management: mechanism of action 150000 180000 100 150000 180000
A. Kumar NCI R01 CA135451-01 7/1/2008 12:00:00 AM 5/31/2013 12:00:00 AM Targeting flip for prostate cancer prevention 207500 303116 100 207500 303116
R. Ludueña DOD W81XWH-05-1-0238 1/31/2005 12:00:00 AM 2/28/2009 12:00:00 AM Development of a novel chemotherapeutic approach to breast cancer 72172 97239 100 72172 97239
R. Ludueña Ziopharm Company 4/1/2008 12:00:00 AM 10/31/2008 12:00:00 AM Interaction of indibulin with tubulin isotypes 27667 35589 100 27667 35589
M. Natarajan NCI 5R01-CA112175-03 12/12/2005 12:00:00 AM 11/30/2009 12:00:00 AM Enhanced apoptosis by targeting protein redox status 127444 174209 100 127444 174209
B. Oyajobi NCI 5K01-CA104180-05 5/26/2004 12:00:00 AM 4/30/2009 12:00:00 AM NF-kB in myeloma cell growth and survival in vivo 146750 158490 100 146750 158490
B. Oyajobi NCI 5P0-CA040035-19 9/1/2006 12:00:00 AM 8/31/2011 12:00:00 AM Effects of tumors on the skeleton (Project 2) 70693 103212 100 70693 103212
S. Padalecki DOD W81XWH-08-1-0287 6/1/2008 12:00:00 AM 5/31/2011 12:00:00 AM Hyaluronic acid as a target for intervention in prostate cancer metastases 125000 182500 100 125000 182500
L. Penalva NIH U01HG004571-01 9/27/2007 12:00:00 AM 6/30/2009 12:00:00 AM Comprehensive identification of encode in the human genome 119835 174959 100 119835 174959
L. Sun NCI 5P01CA040035 9/1/2007 12:00:00 AM 8/31/2009 12:00:00 AM Effects of tumors on the skeleton (Project #3) 86073 125667 100 86073 125667
L. Sun NCI 2R01 CA75253-11A1 7/15/1997 12:00:00 AM 7/31/2009 12:00:00 AM Targeting transforming growth factor beta for cancer treatment 149951 218928 100 149951 218928
L. Sun NCI 5R01CA079683-09A1 1/1/1999 12:00:00 AM 5/31/2009 12:00:00 AM TGF beta receptor and tumor progression 149338 221020 100 149338 221020
Z. Yuan NCI 1R01CA125144-01A2 7/1/2008 12:00:00 AM 7/31/2013 12:00:00 AM The role of Beclin 1/class III PI-3 kinase and p53 in breast cancer 250000 370000 100 250000 370000
Z. Yuan NCI 5R01CA085679-08 6/1/2008 12:00:00 AM 5/31/2009 12:00:00 AM Molecular basis of p3-induction to DNA damage 118785 175802 100 118785 175802